Dipeptide-2
PreclinicalSynthetic dipeptide
Research material. Not for human or animal consumption.
Research overview
Dipeptide-2 is the INCI name for valyl-tryptophan (Val-Trp), a two amino acid peptide used in cosmetic eye-contour formulations aimed at puffiness. Val-Trp is also described in food science as an angiotensin-converting enzyme inhibitory dipeptide. Independent published research on topical use is sparse: most available material is chemical characterisation, computational modelling and supplier application notes rather than controlled studies.
Laboratory, computational, ex vivo or animal model research is the main evidence base.
Questions about Dipeptide-2
PRODUCT QUESTIONSWhat is Dipeptide-2?
Dipeptide 2 is valyl tryptophan, a dipeptide formed from valine and tryptophan. It is small enough to behave more like a simple organic compound than a typical peptide during analysis and formulation.
What research has been published on Dipeptide-2?
Valyl tryptophan has been characterised in nutrition research as an angiotensin converting enzyme inhibitory dipeptide derived from food proteins. Cosmetic suppliers include it in eye area products intended to reduce the appearance of puffiness, but peer reviewed human data on topical performance are limited.
What batch documentation should accompany Dipeptide-2?
Dipeptide-2: Ask for the COA and analytical reports for the batch being quoted. For a dipeptide this small, identity should be confirmed by mass spectrometry or NMR, and the HPLC method should resolve tryptophan and valine left over from synthesis.
How should Dipeptide-2 storage conditions be assessed?
Dipeptide-2 should be kept dry and sealed at room temperature or refrigerated, away from light. The tryptophan side chain is sensitive to light and oxidation, which can cause yellowing in solutions.