CJC-1295 Without DAC / MOD GRF 1–29
Early humanSynthetic GHRH fragment peptide
Research material. Not for human or animal consumption.
Research overview
Mod GRF 1-29, often sold as CJC-1295 without DAC, is the 1-29 fragment of growth hormone-releasing hormone with four amino acid substitutions (D-Ala2, Gln8, Ala15, Leu27). These changes slow enzymatic breakdown and reduce side reactions, extending its half-life beyond sermorelin's, though it remains short-acting. The name causes confusion: the original CJC-1295 carries a drug affinity complex (DAC) that binds albumin and lasts days, and that version was the one studied in published human pharmacology trials.
Limited, exploratory, early phase or small human studies have been identified.
Questions about CJC-1295 Without DAC / MOD GRF 1–29
PRODUCT QUESTIONSWhat is CJC-1295 Without DAC / MOD GRF 1–29?
CJC-1295 Without DAC / MOD GRF 1–29 is a 29 residue GHRH analogue with four substituted positions and no albumin binding group. It differs from the DAC version of the compound, which carries an added reactive linker that binds albumin.
What research has been published on CJC-1295 Without DAC / MOD GRF 1–29?
The best known human data come from studies of the DAC containing version in healthy adults, which showed sustained rises in growth hormone and IGF 1 for days. Evidence for the version without DAC is largely pharmacological and preclinical, so results for one form should not be applied to the other.
What batch documentation should accompany CJC-1295 Without DAC / MOD GRF 1–29?
CJC-1295 Without DAC / MOD GRF 1–29: Ask for the COA and analytical reports for the batch being quoted. Make sure the certificate confirms the material has no DAC group, with intact mass matching the four substitutions, HPLC purity and acetate content.
How should CJC-1295 Without DAC / MOD GRF 1–29 storage conditions be assessed?
Store lyophilised Mod GRF 1 to 29 at −20°C, sealed and protected from light. Like other GHRH fragments it is unstable in solution, so keep reconstituted material cold and use it within days.
Request a quotation
Enquire about CJC-1295 Without DAC / MOD GRF 1–29 and the documentation for the available batch.
Request a quotation